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"Malaria has been haunting mankind since evolution. It has killed more people than all the wars, has greatly influenced our history and geography and has changed many of our genes. During the 3 decades from 1969-2000, hundreds of millions of people were infected with malaria, tens of millions died – mostly in sub-Saharan Africa , millions of households failed to emerge out of poverty as they struggled with catastrophic health expenditures, hundreds of thousands of pregnant women died during delivery due to malaria-related complications, and millions of children were born with low birthweight, potentially leading to early death or lifelong disability; millions of children who survived struggled with learning as they dealt with frequent absenteeism due to multiple episodes of malaria, chronic anaemia, seizures or cognitive impairment – consequences of infection and severe disease; huge blows were dealt to the growth of already weak post-independence national economies, and their attempts to build viable health systems were hampered by lost productivity and high demand for health care. [World Malaria Report 2020]"

"In the first 2 decades of the 21st century, claimed to be a golden era in the history of malaria control, unprecedented scale-up of malaria interventions led to considerable reductions in disease incidence and mortality. These efforts coincided with other trends and changes that have had a positive impact on malaria, including a period of considerable economic growth and development, infrastructure and housing improvements, rapid urbanization, and general improvements in health systems and population health. It had been claimed that by the end of 2019, about 1.5 billion malaria cases and nearly 7.6 million deaths had been averted since the beginning of the century. However, in the later years, progress had stalled.[World Malaria Report 2020]"

"Malaria deaths reduced steadily over the period 2000–2019, from 736 000 in 2000 to 409 000 in 2019. The percentage of total malaria deaths among children aged under 5 years was 84% in 2000 and 67% in 2019. Globally, the malaria mortality rate (i.e. deaths per 100 000 population at risk) reduced from about 25 in 2000 to 12 in 2015 and 10 in 2019, with the slowing of the rate of decline in the latter years. About 95% of malaria deaths globally were in 31 countries. Nigeria (23%), the Democratic Republic of the Congo (11%), the United Republic of Tanzania (5%), Mozambique (4%), Niger (4%) and Burkina Faso (4%) accounted for about 51% of all malaria deaths globally in 2019. Malaria deaths in the WHO African Region reduced by 44%, from 680 000 in 2000 to 386 000 in 2019, and the malaria mortality rate reduced by 67% over the same period, from 121 to 40 deaths per 100 000 population at risk. In the WHO South-East Asia Region, malaria deaths reduced by 74%, from about 35 000 in 2000 to 9 000 in 2019. India accounted for about 86% of all malaria deaths in the WHO South-East Asia Region. [World Malaria Report 2020]"

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